December 8-9, Institut Curie
Chemical biology enables the conception and discovery of powerful molecules to observe and virtually manipulate any cellular process, allowing for addressing biological problems that would otherwise remain elusive. Although the last decade’s advances in chemical biology have led to new discoveries in biology, there are still extraordinary opportunities in further pushing its boundaries. The most useful approaches will enable to interrogate quantitatively and comprehensively living systems at the molecular, cellular and network levels. Beyond academic applications, chemical biology holds great potential for addressing important problems of our world. Small molecules able to restore and correct function in the context of human diseases can potentially have a transformative impact in medicine. Personalized medicine could benefit from a combination of chemical biology, genome and disease biology to establish novel diagnostic tools and alternative therapeutic approaches. Chemical biology has also a major role to play in the development of new renewable energies and sustainable materials, in particular through the combination of knowledge in biosynthetic pathways, metabolic engineering and bioinformatics.
Gautier A, Rodriguez R. PSL. Chemical Biology Symposia First 2016 Edition: When Chemistry and Biology Share the Language of Discovery - Chembiochem. 2017 May 18;18(10):883-887. doi: 10.1002/cbic.201700117